Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Relationship Formation02:12

Relationship Formation

What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
Yeast Signaling01:28

Yeast Signaling

Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
Mate Choice01:20

Mate Choice

Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
Natural Selection and Mating Preferences01:06

Natural Selection and Mating Preferences

The principle of natural selection posits that organisms better adapted to their environment are more likely to survive and reproduce. This principle is closely intertwined with mating preferences, a key aspect of sexual selection, which evolutionary psychologists believe is driven by instincts to propagate one's genes. Such instincts significantly influence mating behaviors and preferences between genders.
Females, due to their biological roles in conception, pregnancy, and nursing, inherently...
Factors Influencing Attraction V: Social Skills01:29

Factors Influencing Attraction V: Social Skills

Social skills play a crucial role in shaping interpersonal interactions and enhancing individuals' ability to navigate various social environments successfully. These skills contribute to personal and professional success, influencing how others perceive and treat individuals. High social skills provide distinct advantages in numerous settings, including romantic relationships, politics, and legal proceedings. In courtroom settings, for instance, defendants who exhibit strong social skills are...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lakartidningen·2026
Same author

Risk of placenta previa in assisted reproductive technology: A Nordic population study with sibling analyses.

PLoS medicine·2025
Same author

Managing Pregnancies of Unknown Location With the M4 Prediction Model or the NICE Algorithm: A Randomised Controlled Trial With Cross-Sectional Diagnostic Accuracy Data.

BJOG : an international journal of obstetrics and gynaecology·2025
Same author

Maternal and perinatal outcomes after implementation of a more active management in late- and postterm pregnancies in Sweden: A population-based cohort study.

PLoS medicine·2025
Same author

Development and validation of a gonadotropin dose selection model for optimized ovarian stimulation in IVF/ICSI: an individual participant data meta-analysis.

Human reproduction update·2024
Same author

Preterm birth in assisted reproduction: the mediating role of hypertensive disorders in pregnancy.

Human reproduction (Oxford, England)·2024

Related Experiment Video

Updated: Jul 4, 2026

Methods of Pairing and Pair Maintenance of New Zealand White Rabbits (Oryctolagus Cuniculus) Via Behavioral Ethogram, Monitoring, and Interventions
10:00

Methods of Pairing and Pair Maintenance of New Zealand White Rabbits (Oryctolagus Cuniculus) Via Behavioral Ethogram, Monitoring, and Interventions

Published on: March 16, 2018

How to promote singletons.

Christina Bergh1

  • 1Sahlgrenska University Hospital, Department of Obsetrics and Gynaecology, Bla Straket 6, 413 45 Göteborg, Sweden. christina.bergh@vgregion.se

Reproductive Biomedicine Online
|July 18, 2008
PubMed
Summary
This summary is machine-generated.

Single embryo transfer (SET) is as effective as double embryo transfer (DET) for live birth rates but significantly reduces multiple births and neonatal problems. This approach ensures healthier outcomes for children born via IVF.

More Related Videos

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos
06:45

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos

Published on: May 29, 2020

Related Experiment Videos

Last Updated: Jul 4, 2026

Methods of Pairing and Pair Maintenance of New Zealand White Rabbits (Oryctolagus Cuniculus) Via Behavioral Ethogram, Monitoring, and Interventions
10:00

Methods of Pairing and Pair Maintenance of New Zealand White Rabbits (Oryctolagus Cuniculus) Via Behavioral Ethogram, Monitoring, and Interventions

Published on: March 16, 2018

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos
06:45

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos

Published on: May 29, 2020

Area of Science:

  • Reproductive Medicine
  • In Vitro Fertilization (IVF)
  • Neonatal Health

Background:

  • In vitro fertilization (IVF) is associated with adverse outcomes in children, primarily due to increased rates of multiple births, prematurity, and neonatal complications.
  • While single embryo transfer (SET) primarily results in singleton births, concerns about reduced birth rates have hindered its widespread adoption.

Purpose of the Study:

  • To evaluate the efficacy and safety of single embryo transfer (SET) compared to double embryo transfer (DET) in IVF.
  • To assess the impact of SET on live birth rates, multiple births, and neonatal outcomes.

Main Methods:

  • Analysis of data from the largest randomized controlled trial comparing SET and DET.
  • Review of observational studies on cleaved embryo and blastocyst transfers.
  • Examination of national data from Sweden and Belgium following legislative changes promoting SET.

Main Results:

  • The largest RCT demonstrated similar cumulative live birth rates for SET and DET, with a near-complete elimination of multiple births.
  • SET significantly reduced severe neonatal problems by 50% compared to DET.
  • Observational studies and national data (Sweden, Belgium) confirm comparable pregnancy and live birth rates with SET, alongside a substantial decrease in multiple births.

Conclusions:

  • Single embryo transfer (SET) is a safe and effective IVF strategy that achieves live birth rates comparable to double embryo transfer (DET) while drastically reducing multiple births and associated neonatal risks.
  • Shifting clinical practice and attitudes towards routine SET is crucial for improving the overall health outcomes of children conceived via IVF.
  • The common goal of delivering healthy, term infants can be more effectively achieved by embracing SET.