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Published on: September 5, 2017
Sudden onset of pseudotuberculosis in humans, France, 2004-05
Pascal Vincent1, Alexandre Leclercq, Liliane Martin
1Institut National de la Santé et de la Recherche Médicale (INSERM), Lille, France.
Abstract:
Cases of Yersinia pseudotuberculosis infection increased in France during the winter of 2004-05 in the absence of epidemiologic links between patients or strains. This increase represents transient amplification of a pathogen endemic to the area and may be related to increased prevalence of the pathogen in rodent reservoirs.
Insights
Yersinia pseudotuberculosis infections rose in France during winter 2004-05. This transient pathogen amplification may stem from increased prevalence in rodent reservoirs.
Area of Science:
- Microbiology
- Epidemiology
- Infectious Diseases
Background:
- Yersinia pseudotuberculosis is an endemic pathogen.
- Increased incidence of Yersinia pseudotuberculosis infections was observed in France during the 2004-05 winter season.
- No clear epidemiologic links were identified between patient cases or bacterial strains.
Purpose of the Study:
- To investigate the cause of the increased Yersinia pseudotuberculosis infections.
- To understand the dynamics of pathogen amplification in the environment.
Main Methods:
- Observational epidemiological study.
- Analysis of infection case data.
- Environmental surveillance (implied).
Main Results:
- A transient increase in Yersinia pseudotuberculosis cases occurred.
- The amplification was not linked to specific patient or strain clusters.
- A potential association with increased pathogen prevalence in rodent reservoirs was suggested.
Conclusions:
- The observed increase in Yersinia pseudotuberculosis infections likely represents transient environmental amplification.
- Rodent populations may play a role in the cyclical prevalence of this pathogen.
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