Related Experiment Video
Updated: Jul 3, 2026

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells
Published on: May 19, 2020
[Central nervous system involvement in Wegener's granulomatosis]
F Jouret1, S Noirhomme, C Grandin
1Service de médecine interne générale, cliniques universitaires de Saint-Luc, université catholique Louvain, avenue Hippocrate, 1200 Bruxelles, Belgique.
Introduction:
Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis associated with c-ANCA antibodies. The involvement of the central nervous system in WG is uncommon and usually caused by in situ vasculitis, intracranial granuloma formation or contiguous invasion from extracranial sites.
Case Report:
Here, we report on a tumour-like expansion of a severe nasosinusal WG into the brain, which was confirmed by brain biopsy examination.
Conclusion:
The positivity of positron emission tomography in our observation supports the potential role of such functional imaging in the staging, as well as in the follow-up of WG.
More Related Videos
08:47Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
Published on: May 8, 2016
10:50Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo
Published on: March 26, 2019
Related Concept Videos
Encephalitis ll: Pathophysiology
Chronic Inflammation: Introduction
Bacterial Meningitis II: Pathophysiology