Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hepatitis

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...

Viral Hepatitis I: Introduction

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Tuberculosis of the Cuboid Bone: An Unfamiliar Manifestation of a Familiar Disease.

Advanced biomedical research·2026

Same author

Assessment of Breastmilk Microbiome Focusing on Probiotics.

Iranian journal of nursing and midwifery research·2026

Same author

Evaluation of Inhaled Colistin/Fosfomycin as an Adjunctive Treatment for Ventilator-Associated Pneumonia: A Preliminary Study.

Health science reports·2025

Same author

Nosocomial Infections in Isfahan Province: A 5-Year Study Based on the National Nosocomial Infections Surveillance.

International journal of preventive medicine·2025

Same author

Detection and Identification of Leishmania major, Leishmania tropica, and Leishmania infantum in Clinical Samples Based on Size Polymorphism of Partially Amplified Ribosomal DNA.

The American journal of tropical medicine and hygiene·2025

Same author

Nosocomial Diarrhea Distribution by <i>Cryptosporidium</i> in Isfahan.

Advanced biomedical research·2025

Search research articles

Related Experiment Video

Updated: Jul 3, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

Hepatitis E virus in Isfahan Province: a population-based study.

Behrooz Ataei¹, Zary Nokhodian, Abbas Ali Javadi

¹Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Ataei@med.mui.ac.ir

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases

|July 5, 2008

Summary

Hepatitis E virus (HEV) seroprevalence in Iran

More Related Videos

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection

Published on: November 7, 2018

Related Experiment Videos

Last Updated: Jul 3, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection

Published on: November 7, 2018

Area of Science:

Epidemiology
Virology
Public Health

Background:

Hepatitis E virus (HEV) is a significant cause of acute viral hepatitis globally.
Limited data exists on HEV epidemiology within Iran.
This study addresses the knowledge gap by assessing HEV seroprevalence in Isfahan Province.

Purpose of the Study:

To determine the seroprevalence of Hepatitis E virus (HEV) infection.
To investigate the distribution of anti-HEV antibodies in Isfahan Province, Iran.

Main Methods:

A cross-sectional study was conducted in 2005.
816 individuals aged 6+ from urban and rural Isfahan were sampled using multistage cluster sampling.
Anti-HEV antibodies were measured via ELISA; statistical analysis used the Chi-square test.

Main Results:

The overall anti-HEV seroprevalence was 3.8%.
Seroprevalence showed an increasing trend with age, from 0.9% (6-9 years) to 8.1% (>50 years).
Significant regional variation was observed, with the highest prevalence in Khomeini Shahr (13.3%).

Conclusions:

HEV seroprevalence in Isfahan Province is lower than previously reported in Iran and the Middle East.
Further research across Iran is recommended to map prevalence and inform prevention strategies.