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Updated: Jul 3, 2026
Nine-Grid Area Division Method: A New Ideal Bone Puncture Region for Percutaneous Vertebroplasty in Lumbar Spine
Published on: August 9, 2024
Percutaneous vertebroplasty in multiple myeloma vertebral involvement
Salvatore Masala1, Giovanni Carlo Anselmetti, Stefano Marcia
1Department of Diagnostic and Molecular Imaging, Interventional Radiology, Nuclear Medicine and Radiation Therapy, University of Rome Tor Vergata, Rome, Italy. salva.masala@tiscali.it
Percutaneous vertebroplasty offers effective pain relief and improved vertebral strength for patients with spinal lesions from multiple myeloma. This minimally invasive procedure demonstrated significant pain reduction and no major complications in a study of 64 patients.
Area of Science:
- Orthopedics
- Oncology
- Interventional Radiology
Background:
- Spinal osteolytic lesions are common in hematologic malignancies like multiple myeloma.
- These lesions can result from direct disease involvement or corticosteroid therapy.
- Pain from these lesions often proves refractory to conventional treatments.
Purpose of the Study:
- To evaluate the effectiveness and safety of percutaneous vertebroplasty.
- To assess its role in treating vertebral pain due to multiple myeloma.
- To determine its impact on vertebral strength and patient outcomes.
Main Methods:
- Percutaneous vertebroplasty was performed on 64 patients with spinal pain from multiple myeloma.
- Patients had pain refractory to conventional therapy and no neurological signs.
- Pain levels and vertebral resistance were assessed pre- and post-procedure, with follow-up at 1 and 6 months.
Main Results:
- A significant reduction in pain scores was observed post-procedure (P<0.01).
- Average pain decreased from 8.04 to 1.82 at 1 month and 1.92 at 6 months.
- No procedure-related complications, such as polymethylmethacrylate leakage or pulmonary embolism, were reported.
Conclusions:
- Percutaneous vertebroplasty is a safe and effective alternative for neoplastic vertebral lesions in hematologic malignancies.
- It provides rapid pain relief and enhances vertebral resistance.
- It can be used synergistically with radiation therapy, especially after failure or recurrence.
