The immunisation of chickens against infectious avian encephalomyelitis

An immune response was induced in chickens vaccinated with the NSW-1 virus by the intramuscular, eye drop, wing web or oral methods. The oral procedure was the most sensitive in inducing an immune response with the lowest dose of virus. The wing web method was the least sensitive. Clinical IAE developed in 1 chicken following intramuscular vaccination. The virus was recovered from the faeces of chickens vaccinated orally with 700 CID50 of the virus from the third to the tenth day after vaccination.