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Related Concept Videos

B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
Humoral Immune Responses01:36

Humoral Immune Responses

Overview
Enlargement of the Plasma Membrane01:22

Enlargement of the Plasma Membrane

Cell division and enlargement are processes that require precise control. The control ensures that cell division cannot proceed unless the cell has grown to a specific size. A spherical, dividing cell requires an approximately 1.6X increase in its surface area to double its volume. The secretory pathway also has a significant role in cell membrane enlargement. Secretory vesicles that bud off from the Golgi apparatus and later fuse with the plasma membrane during exocytosis are a major source of...
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...

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Related Experiment Video

Updated: Jul 3, 2026

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

Plasma cell adaptation to enhance particle acceleration.

M S Ragheb1

  • 1Accelerators Department, Nuclear Research Center, AEA, Cairo, Egypt.

The Review of Scientific Instruments
|July 8, 2008
PubMed
Summary

This study demonstrates a novel plasma cell for particle acceleration and beam driver applications. The preformed plasma, generated via capacitive discharge, exhibits high density and stability, suitable for advanced accelerator designs.

Area of Science:

  • Plasma Physics
  • Accelerator Science
  • Beam Physics

Background:

  • Plasma acceleration offers a promising avenue for future particle accelerators.
  • Developing stable and controllable plasma environments is crucial for beam injection and manipulation.

Purpose of the Study:

  • To construct and characterize a plasma cell for particle acceleration.
  • To investigate a multicell design for beam driver applications.
  • To experimentally validate the proposed plasma cell configurations.

Main Methods:

  • Symmetrically driven capacitive audio frequency discharge used to create preformed plasma.
  • Langmuir double probe utilized for electron temperature measurements.
  • Experimental demonstration with two plasma cell configurations using various gases (Ar, He, H2).

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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles

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Related Experiment Videos

Last Updated: Jul 3, 2026

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation
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Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation

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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
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Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles

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Main Results:

  • Achieved high plasma density (10^11–10^15 cm^-3) and electron temperature (1–16 eV).
  • Optimal plasma parameters obtained at 950 V and 20 kHz, with ionization efficiency exceeding 100% for Ar and He.
  • Demonstrated uniform and stable plasma column suitable for particle acceleration and long-distance electron beam propagation.

Conclusions:

  • The developed plasma cell meets conditions for enhanced particle acceleration.
  • The design is extendable for particle acceleration and beam driver applications.
  • Specific gases (H2, Ar) are suitable for low-density and high-density beam drivers, respectively.