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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

[Intracranial atherosclerosis]

Pablo Del Saz-Saucedo1, José Francisco Maestre-Moreno, Juan Francisco Arenillas-Lara

  • 1Servicio de Neurología, Hospital Universitario Virgen de las Nieves, Granada, España. pablodelsaz@gmail.com

Medicina Clinica
|July 8, 2008
PubMed

Insights

Intracranial atheromatosis, a leading cause of stroke, is increasingly diagnosed. This review covers its natural history and treatment options, highlighting the need for better therapies.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Cerebrovascular Disease

Context:

  • Intracranial atheromatosis is a significant and increasingly recognized cause of stroke.
  • Advances in non-invasive imaging have improved diagnosis and highlighted its prevalence.
  • Previously underdiagnosed, it now demands greater clinical and research attention.

Purpose:

  • To review the natural history of intracranial atheromatosis.
  • To discuss current and potential therapeutic strategies for intracranial atheromatosis.
  • To identify markers of poor outcome in patients with intracranial atheromatosis.

Summary:

  • Intracranial atheromatosis, a major cause of stroke, is now frequently diagnosed due to advanced imaging.
  • Research focuses on identifying prognostic markers and understanding mechanisms of cerebral ischemia.
  • Current medical and endovascular treatments are limited, necessitating further therapeutic development.

Impact:

  • Improved understanding of intracranial atheromatosis will aid clinical decision-making.
  • This review provides a foundation for developing more effective treatments for stroke prevention and management.
  • Highlights the need for enhanced therapeutic options for this prevalent cerebrovascular condition.

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