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Published on: December 20, 2024
[Dishen Qufeng Decoction for treating allergic rhinitis: a randomized controlled trial]
Wei-rong Zhu1, Shou-jie Zhang, De-hou Deng
1Department of Traditional Chinese Medicine, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China.
Summary
Dishen Qufeng Decoction (DSQFD) effectively treats allergic rhinitis by improving symptoms and reducing eosinophils. This traditional Chinese medicine shows comparable efficacy to cetirizine.
Area of Science:
- Integrative Medicine
- Pharmacology
- Immunology
Context:
- Allergic rhinitis is a prevalent condition affecting quality of life.
- Current treatments like cetirizine have limitations.
- Traditional Chinese Medicine (TCM) offers alternative therapeutic approaches.
Purpose:
- To evaluate the clinical efficacy of Dishen Qufeng Decoction (DSQFD) for allergic rhinitis.
- To compare DSQFD's effectiveness against cetirizine, a standard antihistamine.
- To assess the impact of DSQFD on allergic rhinitis symptoms, nasal signs, and peripheral blood eosinophil counts.
Summary:
- A randomized controlled trial involved 60 allergic rhinitis patients, divided into DSQFD and cetirizine groups.
- Patients received oral DSQFD or cetirizine, with symptom and sign assessments before and after treatment.
- DSQFD demonstrated significant improvement in allergic rhinitis symptoms and nasal signs, with a total response rate of 83.3%.
Impact:
- DSQFD shows comparable therapeutic effects to cetirizine in managing allergic rhinitis.
- The study supports DSQFD as a viable traditional Chinese herbal medicine option for allergic rhinitis treatment.
- Further research can explore DSQFD's mechanisms of action and long-term effects.