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Distribution, gene expression, and functional role of EphA4 during ossification

Chisa Kuroda1, Satoshi Kubota, Kazumi Kawata

  • 1Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8525, Japan.

Biochemical and Biophysical Research Communications
|July 8, 2008
PubMed
Summary

The EphA4 receptor tyrosine kinase plays a key role in bone development. This study reveals EphA4 is crucial for ossification, impacting osteoblasts and hypertrophic chondrocytes in the growth plate.

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