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An immunisation strategy for the protection of cattle against alcelaphine herpesvirus-1-induced malignant catarrhal

David M Haig1, Dawn Grant, David Deane

  • 1Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik EH26 0PZ, Scotland, UK. david.haig@nottingham.ac.uk

Vaccine
|July 8, 2008
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Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.