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Related Experiment Video

Updated: Jul 3, 2026

Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar

Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar

Published on: May 30, 2025

Localized juvenile spongiotic gingival hyperplasia.

Julia Yu Fong Chang¹, Harvey P Kessler, John M Wright

¹School of Dentistry, National Taiwan University College of Medicine.

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics

|July 8, 2008

Summary

This study identifies a distinct gingival hyperplasia in young patients, characterized by papillary overgrowth and specific histologic features. The proposed term is localized juvenile spongiotic gingival hyperplasia.

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Area of Science:

Oral pathology
Pediatric dentistry
Dermatology

Background:

Gingival hyperplasia can present in various forms.
Accurate classification is crucial for appropriate management.
Previous descriptions may lack specificity for certain pediatric cases.

Purpose of the Study:

To describe a unique cohort of inflammatory gingival hyperplasia in young patients.
To establish characteristic clinical and histopathological features.
To propose a more accurate nomenclature for this distinct entity.

Main Methods:

Retrospective case series analysis of 52 patients.
Clinical data collection including age, sex, ethnicity, and lesion location.
Histopathological examination of biopsy specimens.

Main Results:

Average patient age 11.8 years; 2.3:1 female predominance.
Lesions predominantly on anterior maxillary gingiva (81%).
Classic presentation: papillary, pedunculated, red, easily bleeding overgrowth with specific epithelial changes.

Conclusions:

The described lesion represents a distinct subtype of gingival hyperplasia.
Proposed term: localized juvenile spongiotic gingival hyperplasia.
This designation reflects the unique clinical and histological findings.