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The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.

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Related Experiment Video

Updated: Jul 3, 2026

Whole Mount Dissection and Immunofluorescence of the Adult Mouse Cochlea
12:02

Whole Mount Dissection and Immunofluorescence of the Adult Mouse Cochlea

Published on: January 1, 2016

Development of the mouse cochlea database (MCD).

Peter A Santi1, Ian Rapson, Arne Voie

  • 1Department of Otolaryngology, University of Minnesota, Minneapolis, MN 55455, USA. psanti@umn.edu

Hearing Research
|July 8, 2008
PubMed
Summary
This summary is machine-generated.

The mouse cochlea database (MCD) offers interactive 2D and 3D images for studying mouse cochlear anatomy. This resource aids in data mining and understanding morphometric parameters in normal and mutant mice.

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Related Experiment Videos

Last Updated: Jul 3, 2026

Whole Mount Dissection and Immunofluorescence of the Adult Mouse Cochlea
12:02

Whole Mount Dissection and Immunofluorescence of the Adult Mouse Cochlea

Published on: January 1, 2016

Cochlear Surface Preparation in the Adult Mouse
09:51

Cochlear Surface Preparation in the Adult Mouse

Published on: November 6, 2019

Long-term Time Lapse Imaging of Mouse Cochlear Explants
10:43

Long-term Time Lapse Imaging of Mouse Cochlear Explants

Published on: November 2, 2014

Area of Science:

  • Anatomy
  • Bioimaging
  • Genetics

Background:

  • The mouse cochlea is a critical model for auditory research.
  • Understanding its intricate anatomy is essential for studying hearing function and disorders.
  • Existing resources for mouse cochlear anatomy are limited.

Purpose of the Study:

  • To create a comprehensive, interactive image database of the mouse cochlea.
  • To facilitate learning of cochlear anatomy and data mining.
  • To establish a new paradigm for understanding cochlear morphometrics.

Main Methods:

  • Acquisition of serial 2D image stacks using orthogonal plane fluorescence optical microscopy (OPFOS).
  • Generation of 3D reconstructions from 2D image stacks.
  • Virtual resectioning for quantitative assessment of cochlear structures.

Main Results:

  • The mouse cochlea database (MCD) provides viewable 2D image stacks, atlases, and orthogonal sections.
  • Interactive 3D visualizations include direct volume renderings, movies, and isosurface reconstructions.
  • Quantitative cross-sections of the scala media were generated for morphometric analysis.

Conclusions:

  • The MCD is the first comprehensive image resource for the mouse cochlea.
  • It serves as a valuable tool for anatomical study and data mining.
  • The database advances the understanding of cochlear structures in normal and mutant mice.