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Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery

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Spindle cell lipoma breast.

Reema Jaffar¹, Sufian Zaheer, Shaista M Vasenwala

¹Department of Pathology, J.N.M.C.H., A.M.U., Aligarh, India.

Indian Journal of Pathology & Microbiology

|July 8, 2008

Summary

Spindle cell lipoma is a rare breast tumor that can mimic other spindle cell masses. Immunohistochemistry, particularly CD 34 reactivity, aids in its diagnosis.

Area of Science:

Oncology
Pathology
Radiology

Background:

Spindle cell lipoma (SCL) is a benign soft tissue tumor, rarely found in the breast.
Distinguishing SCL from primary mammary spindle cell tumors can be challenging.
Early detection of breast masses is crucial for effective management.

Observation:

A 48-year-old woman presented with an incidentally detected 3-cm mass in the left breast during routine mammography.
The mass was well-circumscribed, solitary, and nontethered, located deep within the breast tissue.
Initial imaging suggested a potential primary mammary spindle cell tumor.

Findings:

Histopathological examination revealed spindle cells within the mass.
Immunohistochemical analysis showed these spindle cells were immunoreactive to CD 34.

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The cells were nonreactive to desmin and smooth muscle actin, ruling out smooth muscle differentiation.

Implications:

CD 34 positivity in spindle cells is a key indicator for diagnosing spindle cell lipoma in the breast.
This case highlights the importance of immunohistochemistry in differentiating rare breast tumors.
Accurate diagnosis of spindle cell lipoma prevents misclassification and unnecessary aggressive treatment.