[A control study of clomipramine and amitriptyline for treating obsessive-compulsive disorder]

This paper reported a comparative study of clomipramine (n = 21) and amitriptyline (n = 18) for treatment OCD. The improvement rate of clomipramine and amitriptyline was 95.2% and 55.6%, respectively (P less than 0.01). The decreased scores of obsessive-compulsive and depressive factors of SCL-90 of clomipramine were higher than amitriptyline. The results showed that clomipramine has better therapeutic effects and less side-effects than amitriptyline.