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Updated: Jul 3, 2026

Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
Rapid detection of helicobacter pylori by endoscopic brush cytology and comparison with histopathology
1Department of Patholgy, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu. jasminakhter2003@yahoo.com
Objectives:
The main objective of this study was to assess antral brush cytology as an alternate approach for the diagnosis of H. pylori infection as compared to histopathology.
Methods:
75 cases with diagnosis of antral gastritis underwent endoscopic antral biopsy as well as antral brushing cytology was included irrespective of age and sex. Cytological slides were stained with Giemsa stain & biopsy slides were stained with H&E and Giemsa stain. Correlation was done between cytological smear slides and biopsy slides.
Results:
Among 75 cases, H. pylori were positive in 55 (73.4%) cases of biopsy specimens while in brush cytology it was positive in 48 (64%) cases. In 45 (60%) of 75 cases, H. pylori was seen in both biopsy and brush cytology.
Conclusion:
Endoscopic brush cytology provides an accurate, inexpensive and easy technique in the rapid detection of H.pylori infection.
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