Related Experiment Video
Updated: Jul 3, 2026

07:51
Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
Published on: August 1, 2025
Priapism, ecstasy, and marijuana: is there a connection?
Quan T Tran1, Robyn A Wallace, Esther H A Sim
1School of Medicine, University of Queensland, Brisbane, Queensland 4006, Australia. s4070655@student.uq.edu.au
Advances in Urology
|July 8, 2008
Summary
Priapism, a medical emergency, can be drug-induced. This study explores the potential for priapism caused by combining ecstasy and marijuana, a combination not previously reported.
Area of Science:
- Urology
- Pharmacology
- Toxicology
Background:
- Priapism is a prolonged erection, a urological emergency with diverse causes.
- Drug-induced priapism is a recognized but complex clinical entity.
- The combination of ecstasy and marijuana has not been previously linked to priapism.
Observation:
- This study addresses the lack of documented cases of priapism resulting from the combined use of ecstasy and marijuana.
- It focuses on the potential physiological mechanisms underlying acute drug-induced priapism from these specific substances.
Findings:
- The study speculates on the potential mechanisms through which the co-ingestion of ecstasy and marijuana may lead to priapism.
- It highlights the need for further research into the pharmacological interactions of these illicit substances.
Implications:
- This research may inform clinical awareness regarding the potential for priapism in individuals using both ecstasy and marijuana.
- Understanding these mechanisms could aid in the diagnosis and management of drug-induced priapism.
- It underscores the importance of considering polydrug use in the etiology of priapism.
Related Concept Videos
Hallucinogens and Psychedelics
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
CNS Stimulants: Psychedelic Agents
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its effects by...
Stimulants
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
An Overview of Psychoactive Drugs
Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...

