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[Post-prandial hyperglycemia in type 2 diabetes patients]
André Luiz Cruzes1, Cláudia Elaine T Bosco, Elaine V Pandini
1Departamento de Endocrinologia, Associação de Diabetes Juvenil, Birigui, SP, Brasil. alcruzes@uol.com.br
Arquivos Brasileiros De Endocrinologia E Metabologia
|July 8, 2008
Summary
Continuous glucose monitoring (CGM) showed higher glucose excursions after breakfast in type 2 diabetes patients. CGM is safe and effective for monitoring glucose control.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Diabetes Research
Background:
- Type 2 diabetes management requires effective glucose monitoring.
- Continuous glucose monitoring systems (CGMS) offer insights into glycemic fluctuations.
Purpose of the Study:
- Evaluate post-prandial subcutaneous glucose excursions using CGMS.
- Analyze correlations between subcutaneous glucose, capillary glycemia, and HbA1c.
- Assess the effectiveness, safety, and tolerability of CGMS in type 2 diabetes patients.
Main Methods:
- Analysis of 40 type 2 diabetes patients with HbA1c ≤ 7.3%, on oral agents, and diagnosed <10 years.
- 72-hour CGMS monitoring.
- Comparison of CGMS data with HbA1c and capillary glucose levels.
Main Results:
- Statistically significant higher subcutaneous glucose excursion at breakfast compared to dinner.
- Higher subcutaneous glucose excursion/meal carbohydrate ratio observed at breakfast.
- No significant correlation found between subcutaneous glucose, capillary glycemia, and HbA1c.
- CGMS use was associated with no complications.
Conclusions:
- Subcutaneous glucose excursions are more pronounced after breakfast in this patient cohort.
- No significant correlations were identified between HbA1c and glycemic control parameters measured by CGMS.
- CGMS demonstrated efficiency, safety, and good tolerability in the studied type 2 diabetes patients.
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