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Updated: Jul 3, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice
Published on: January 25, 2016
[Melatonin effects on the female genital system: a brief review]
Carla C Maganhin1, Adriana Aparecida Ferraz Carbonel, Juliana Halley Hatty
1Universidade Federal de São Paulo - Escola Paulista de Medicina (UNIFESP/EPM), São Paulo, SP.
Abstract:
Melatonin is secreted by the pineal gland and this is linked to the day/night cycle. It is an antioxidant and plays a fundamental role in the regulation of the jet-lag stage, in several physiological reactions and in control of the biologic rhythm. Human melatonin has an important influence on the female genital system. In fact, melatonin may influence production and action of steroids, modifying cellular signalization on the target tissue. There are many evidences that the melatonin therapy may be interfering with neoplasia development, mainly of the estrogen-dependent tumor. This paper aims to analyze the actions of melatonin on the neuroendocrine, immunological and cardiovascular systems, as well as on the reproductive function.
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