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Updated: Jul 3, 2026
Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs
Published on: July 5, 2024
A modified technique for the surgical correction of urethral diverticula using a porcine xenograft
James W S Lee1, Stergios K Doumouchtsis, Michelle M Fynes
1Department of Pelvic Reconstructive Surgery and Urogynaecology, 4th Floor Lanesborough Wing, St. George's Hospital, Blackshaw Road, London SW17 0RE, UK.
Abstract:
We report a case of urethral diverticulectomy re-enforced with a porcine xenograft to prevent the risk of recurrence or fistula in the presence of a large urethral communication. The use of porcine small intestinal submucosal xenograft (SIS, Surgisis, Cook, Ireland) material has a low graft rejection rate and erosion is rare as the material is degraded after 3 to 6 months. In this case, xenograft achieved tension-free closure of the urethral defect without any postoperative complications.
