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Published on: October 17, 2013
Current status of the mechanical valve and bioprosthesis in Japan
Shigehiko Tokunaga1, Ryuji Tominaga
1The Department of Cardiovascular Surgery, Kyushu University Hospital, 3-1-1 Maidashi, Fukuoka, 812-8582, Japan. shiget@heart.med.kyushu-u.ac.jp
Insights
The 2006 guidelines favor bioprosthetic valves for aortic valve replacement due to improved durability and patient factors. Mitral valve repair is increasingly preferred over replacement.
Area of Science:
- Cardiology
- Cardiac Surgery
- Biomedical Engineering
Background:
- The American College of Cardiology/American Heart Association (ACC/AHA) revised valvular heart disease management guidelines in 2006.
- Previous guidelines were established in 1998, necessitating an update based on new evidence and technologies.
Purpose of the Study:
- To review the 2006 ACC/AHA guidelines for valvular heart disease management.
- To compare current trends in mechanical valve versus bioprosthesis selection with previous practices.
- To describe the current status of valvular heart disease treatment based on the new guidelines.
Main Methods:
- Review of the 2006 ACC/AHA guidelines for valvular heart disease.
- Comparative analysis of valve selection trends (mechanical vs. bioprosthesis) in aortic and mitral valve replacement between the US and Japan.
- Examination of factors influencing valve choice, including patient age, warfarin therapy acceptance, and reoperation risks.
Main Results:
- A trend towards bioprosthetic valves in aortic valve replacement (AVR) in the US, attributed to lower deterioration rates, decreased reoperation risks, older patient populations, reluctance for warfarin therapy, and observed survival benefits.
- Increasing use of tissue valves in Japan, driven by an aging population and similar factors as in the US.
- Continued preference for mechanical valves over bioprostheses for mitral valve replacement in both the US and Japan.
- A significant increase in mitral valve repair cases compared to mitral valve replacement.
Conclusions:
- Bioprosthetic valves are increasingly favored for AVR, supported by improved outcomes and patient considerations.
- Patient-centered decision-making, involving thorough discussion of risks, benefits, and lifestyle implications, is crucial for selecting prosthetic valves.
- Mitral valve repair is becoming a more common alternative to valve replacement.
Abstract:
The American College of Cardiology/American Heart Association guidelines for the management of patients with valvular heart disease were revised in 2006. These guidelines are introduced in this review, and the current status of the mechanical valve, bioprosthesis, and treatment of valvular heart disease are described based on the new guidelines as compared with the guidelines of 1998. The trend in valve selection in aortic valve replacement in the United States has been toward bioprosthesis, away from the mechanical valve. The reasons are: 1) current bioprostheses appear to have lower rates of structural valve deterioration, 2) the risks of reoperation have continued to decrease, 3) patients undergoing AVR today represent an older population than those in studies in randomized trials, 4) young patients undergoing AVR are often reluctant to accept warfarin therapy, 5) some large comparative trials have shown apparent survival benefit for patients receiving bioprostheses. In Japan, the use of tissue valves has been increasing and may continue to increase owing to the nation's aging population and to the reasons mentioned above. However, more patients received mechanical valves than bioprostheses for mitral valve replacement both in the United States and in Japan. The number of mitral valve repair cases has increased more than that of valve replacement. In selection of valve prosthesis for valve surgery, it is important that patients should decide by themselves based on mutual respect and trust between patient and doctor, with thorough discussion of the possibility of redo surgery and its risks, life-long warfarin intake, quality of life, and the patient's lifestyle and outlook on life.
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