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The Philadelphia High-School STD Screening Program: key insights from dynamic transmission modeling.
David N Fisman1, C Victor Spain, Melinda E Salmon
1Research Institute of the Hospital for Sick Children, Toronto, Ontario, Canada. david.fisman@sickkids.ca
Sexually Transmitted Diseases
|July 9, 2008
Summary
Screening high school students for Chlamydia trachomatis is cost-effective. Including males in the Philadelphia high-school STD Screening Program (PHSSP) improves effectiveness and economic attractiveness, reducing overall disease burden.
Area of Science:
- Public Health
- Epidemiology
- Health Economics
Background:
- The Philadelphia high-school STD Screening Program (PHSSP) has reduced Chlamydia trachomatis prevalence in females.
- The program's cost-effectiveness, particularly with male inclusion, requires assessment.
Purpose of the Study:
- To evaluate the cost-effectiveness of the PHSSP.
- To quantify the impact of including male students in screening.
Main Methods:
- A dynamic transmission model (susceptible-infectious-resistant-susceptible framework) was utilized.
- The model was parameterized with PHSSP data and literature findings.
- Projections included disease burden, quality-adjusted survival, and costs.
Main Results:
- High-school screening is highly cost-effective in Philadelphia.
- Including males enhances program effectiveness and economic attractiveness.
- Increased screening coverage decreases net societal costs due to reduced transmission.
Conclusions:
- The PHSSP is highly cost-effective compared to other interventions.
- Involving males significantly boosts the program's effectiveness and cost-effectiveness.
- Dynamic transmission modeling is crucial for evaluating such public health programs.
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