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Related Experiment Video

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A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

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Hepatitis induced by Teucrium viscidum.

Wing Tat Poon¹, Tai Lin Chau, Chi Kong Lai

¹Toxicology Reference Laboratory, Department of Pathology, Princess Margaret Hospital, Hong Kong, Hong Kong. poonwt@ha.org.h

Clinical Toxicology (Philadelphia, Pa.)

|July 9, 2008

Summary

A woman developed acute hepatitis after consuming Teucrium viscidum, an herb used in Chinese medicine. This case highlights the potential hepatotoxicity of Teucrium viscidum, similar to germander.

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Area of Science:

Hepatology
Integrative Medicine
Herbal Medicine Safety

Background:

Chinese medicine is widely used in Hong Kong alongside Western medicine.
Concerns exist regarding the scientific validation and potential toxicity of many traditional Chinese herbs.
Teucrium viscidum is an infrequently used herb in traditional Chinese medicine.

Observation:

A 51-year-old woman presented with jaundice, nausea, vomiting, and elevated liver enzymes.
She had consumed an herbal remedy containing Teucrium viscidum for low back pain.
Liver enzyme levels normalized two months after discontinuing the herbal remedy.

Findings:

This case report is the first to suggest a link between Teucrium viscidum ingestion and acute hepatitis.
Teucrium viscidum contains teucvin, a compound found in other hepatotoxic Teucrium species.
The observed hepatotoxicity is similar to that caused by Teucrium chamaedrys (germander).

Implications:

Teucrium viscidum should be considered a potential cause of drug-induced liver injury.
Further scientific investigation into the safety and efficacy of Teucrium viscidum is warranted.
Clinicians should inquire about herbal remedy use in patients presenting with unexplained hepatitis.