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08:19
Murine Hind Limb Explant Model for Studying the Mechanobiology of Achilles Tendon Impingement
Published on: December 8, 2023
Adiposity and tendinopathy
Disability and Rehabilitation
|July 9, 2008
Summary
Central adiposity (excess body fat around the waist) may be a significant intrinsic risk factor for tendon injuries (tendinopathy). Further research is needed to understand this link and potential underlying mechanisms.
Area of Science:
- Orthopedics
- Sports Medicine
- Biomedical Science
Background:
- Tendon injuries (tendinopathy) are common in active and inactive individuals, with unknown causes.
- Extrinsic factors like load influence tendinopathy prevalence.
- Intrinsic factors including genetics, biomechanics, and body composition are increasingly recognized as contributors.
Purpose of the Study:
- To review the association between tendinopathy and body composition, particularly central adiposity.
- To evaluate the strength of evidence supporting this association.
- To explore potential biological mechanisms linking adiposity and tendon pathology.
Main Methods:
- Literature review of studies investigating tendinopathy and body composition.
- Analysis of existing research to assess the strength of the association.
- Discussion of potential mechanisms underlying the observed relationship.
Main Results:
- A notable association exists between tendon health and adiposity, with central adiposity being particularly relevant.
- The current evidence suggests this association warrants further in-depth investigation.
Conclusions:
- Adiposity, especially central adiposity, may interact with tendon pathology.
- Adiposity could be a critical intrinsic risk factor for tendinopathy.
- This risk may be actualized in conjunction with other intrinsic (e.g., diabetes) and extrinsic (e.g., mechanical load) factors.
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