Cutaneous alternariosis in a kidney transplantation recipient: report of a case

Gabriella Calabrò1, Massimiliano Nino, Lucia Gallo

  • 1Sezione di Dermatologia clinica, allergologica e venereologica, Dipartimento di Patologia Sistematica, Universita degli Studi di Napoli Federico II, Napoli, Italy. gcalabro@unina.it

Insights

Phaeohyphomycosis, a fungal infection, can be caused by Alternaria alternata. This case highlights a rare skin infection in an immunocompromised patient, emphasizing early diagnosis and treatment.

Area of Science:

  • Mycology
  • Dermatology
  • Infectious Diseases

Background:

  • Phaeohyphomycoses are infections caused by darkly pigmented fungi.
  • Dematiaceous fungi, particularly Alternaria species, are the primary agents.
  • Risk factors include immunosuppression, local wounds, and systemic diseases.

Observation:

  • A rare case of cutaneous phaeohyphomycosis caused by Alternaria alternata is presented.
  • The patient was immunocompromised, presenting with unusual clinical aspects.
  • The infection showed a favorable response to therapeutic intervention.

Findings:

  • Alternaria alternata is identified as the causative agent of phaeohyphomycosis.
  • The clinical presentation of cutaneous alternariosis was rare and noteworthy.
  • Successful treatment was achieved, indicating therapeutic efficacy.

Implications:

  • Highlights Alternaria species as potential opportunistic pathogens.
  • Stresses the importance of considering fungal infections in immunocompromised patients.
  • Aids in the differential diagnosis of granulomatous or ulcerative dermatological lesions.

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