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Updated: Jul 3, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
Cutaneous alternariosis in a kidney transplantation recipient: report of a case
Gabriella Calabrò1, Massimiliano Nino, Lucia Gallo
1Sezione di Dermatologia clinica, allergologica e venereologica, Dipartimento di Patologia Sistematica, Universita degli Studi di Napoli Federico II, Napoli, Italy. gcalabro@unina.it
Abstract:
Phaeohyphomycoses are induced by dematiaceous or darkly pigmented fungi. Alternaria species are the most important causative agents. Factors such as immunosuppression, local wounds or systemic disease are generally present. We report a case of phaeohyphomycosis induced by Alternaria alternata in an immunocompromised patient. The main interest in this case is the rareness of the cutaneous alternariosis and of its clinical aspects and the good response to therapy. Recognition of Alternaria spp. as potential opportunistic pathogens is important for the differential diagnosis of dermatological lesions, such as granulomatous or ulcerative lesions in immunocompromised patients.
Insights
Phaeohyphomycosis, a fungal infection, can be caused by Alternaria alternata. This case highlights a rare skin infection in an immunocompromised patient, emphasizing early diagnosis and treatment.
Area of Science:
- Mycology
- Dermatology
- Infectious Diseases
Background:
- Phaeohyphomycoses are infections caused by darkly pigmented fungi.
- Dematiaceous fungi, particularly Alternaria species, are the primary agents.
- Risk factors include immunosuppression, local wounds, and systemic diseases.
Observation:
- A rare case of cutaneous phaeohyphomycosis caused by Alternaria alternata is presented.
- The patient was immunocompromised, presenting with unusual clinical aspects.
- The infection showed a favorable response to therapeutic intervention.
Findings:
- Alternaria alternata is identified as the causative agent of phaeohyphomycosis.
- The clinical presentation of cutaneous alternariosis was rare and noteworthy.
- Successful treatment was achieved, indicating therapeutic efficacy.
Implications:
- Highlights Alternaria species as potential opportunistic pathogens.
- Stresses the importance of considering fungal infections in immunocompromised patients.
- Aids in the differential diagnosis of granulomatous or ulcerative dermatological lesions.
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