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Impact of congenital talipes equinovarus etiology on treatment outcomes
Christina A Gurnett1, Stephanie Boehm, Anne Connolly
1Department of Orthopedic Surgery, Washington University School of Medicine, One Children's Place, St Louis, MO 63110, U.S.A. gurnettc@neuro.wustl.edu
Insights
Congenital talipes equinovarus (CTEV) with other birth defects requires more casts and has higher recurrence than idiopathic CTEV. However, the Ponseti method remains effective for non-idiopathic CTEV, with low surgery rates.
Area of Science:
- Pediatric Orthopedics
- Genetics
- Developmental Biology
Background:
- Congenital talipes equinovarus (CTEV) is often idiopathic, but associated malformations can influence treatment.
- Understanding the prevalence of non-idiopathic CTEV and its impact is crucial for effective management.
Purpose of the Study:
- To determine the prevalence of associated malformations, chromosomal abnormalities, or genetic syndromes in CTEV patients.
- To compare treatment outcomes between idiopathic CTEV and non-idiopathic CTEV using the Ponseti method.
Main Methods:
- Retrospective analysis of 357 children diagnosed with CTEV.
- Comparison of treatment parameters including casting, recurrence rates, and surgical intervention between idiopathic and non-idiopathic groups.
- Minimum 2-year follow-up for all treated patients.
Main Results:
- Non-idiopathic CTEV was present in 24% of patients, with nervous system disorders being most common (54%).
- Children with non-idiopathic CTEV required significantly more casts (5.3 vs 4.6; p=0.016) and had a higher recurrence rate (14.9% vs 4%; p=0.009).
- No significant difference was found in the need for extensive surgery (8.5% vs 2.7%; p=0.096).
Conclusions:
- Non-idiopathic CTEV, while presenting unique challenges, can be effectively treated with the Ponseti method.
- Early intervention and consistent application of the Ponseti method yield favorable outcomes, even in complex cases.
- The Ponseti method demonstrates efficacy in managing both idiopathic and non-idiopathic congenital talipes equinovarus, with low surgical intervention rates.
Abstract:
Although congenital talipes equinovarus (CTEV) is often idiopathic, additional birth defects occur in some patients that may have an impact on the treatment of this disorder. The purpose of this study was to determine the prevalence of associated malformations, chromosomal abnormalities, or known genetic syndromes, and to compare treatment outcomes of children with idiopathic CTEV with children with non-idiopathic CTEV. Of 357 children evaluated, 273 (76%) had idiopathic CTEV (179 males, 94 females; mean age 2 y 1 mo [SD 1 y 2 mo], range 0-18 y) and 84 (24%) had non-idiopathic CETV (51 males, 33 females; mean age 2 y 5 mo [SD 2 y], range 0-16 y). Disorders affecting the nervous system were found in 46 (54%) children with non-idiopathic CTEV. In a subgroup of patients treated entirely at our institution (n=196), children with non-idiopathic CTEV (n=47) required more casts for correction than those with idiopathic CTEV (n=149; 5.3 vs 4.6; p=0.016). There was also a greater risk of recurrence in non-idiopathic CTEV (14.9% vs 4%; p=0.009), but no significant difference in the need for extensive surgery (2.7% vs 8.5%; p=0.096). Treatment was initiated at a mean age of 13 weeks (range 1 wk to 2 y 6 mo) for both idiopathic and non-idiopathic patients, and treatment was assessed during a minimum 2-year follow-up. Non-idiopathic CTEV can be successfully treated with the Ponseti method of serial casting, with low recurrence rates or need for surgery.
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