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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
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Home intravenous antibiotic therapy
1Department of Medicine, Section of Infectious Disease, Methodist Hospital and Park Nicollet Medical Center, Minneapolis, Minnesota, USA.
International Journal of Antimicrobial Agents
|September 1, 1992
Summary
Home intravenous antibiotic therapy offers a cost-effective alternative to inpatient care for select patients. This approach requires careful patient selection, education, and follow-up for successful outcomes.
Area of Science:
- Infectious Diseases
- Pharmacology
- Health Economics
Background:
- Rising healthcare costs necessitate exploring alternatives to prolonged in-hospital treatment.
- Intravenous (IV) therapy is crucial for managing complex infections but often requires extended hospital stays.
- Home or outpatient IV therapy programs offer a potential solution for selected patients.
Purpose of the Study:
- To explore the development and implementation of home or outpatient IV antibiotic therapy programs.
- To highlight the importance of a multidisciplinary team approach in managing IV therapy outside the hospital.
- To discuss patient selection criteria, educational strategies, and follow-up protocols for successful IV therapy programs.
Main Methods:
- Review of existing literature and clinical practices regarding home and outpatient IV antibiotic therapy.
- Emphasis on the essential components of successful IV therapy programs: team approach, patient selection, education, and follow-up.
- Discussion of the evolving landscape of IV therapy, including its application in acquired immune deficiency syndrome (AIDS) and the impact of new oral antibiotics.
Main Results:
- Home and outpatient IV therapy programs are viable alternatives for patients who no longer require intensive inpatient care.
- Successful implementation hinges on meticulous patient selection, comprehensive patient and caregiver education, and robust follow-up mechanisms.
- The demand for IV anti-infective programs is expected to increase for acquired immune deficiency syndrome (AIDS)-related infections.
Conclusions:
- Home and outpatient IV antibiotic therapy can reduce healthcare costs while maintaining treatment efficacy for selected patients.
- The shift towards oral antibiotics for certain infections may decrease the overall need for IV therapy, but specialized programs remain vital.
- Future IV anti-infective programs will likely focus more on complex conditions like those associated with AIDS.
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