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Curcuminoid-Mediated Antimicrobial Photodynamic Therapy on a Murine Model of Oral Candidiasis

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Management of candiduria.

B Joseph Guglielmo¹, M L Stoller, R A Jabos

¹Division of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, CA 94143-0622, USA.

International Journal of Antimicrobial Agents

|June 1, 1994

Summary

Candiduria, a fungal urinary tract infection, is rising due to factors like broad-spectrum antibiotics. Optimal management remains unclear, but catheter removal and specific antifungal treatments are key for high-risk patients.

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Area of Science:

Infectious Diseases
Mycology
Urology

Background:

Candiduria, a fungal urinary tract infection, is increasingly prevalent.
Factors contributing to its rise include broad-spectrum antibacterial use and immunosuppression.
The optimal management strategy for candiduria is not well-defined.

Purpose of the Study:

To review the current understanding and management of candiduria.
To highlight challenges in defining and treating fungal urinary tract infections.
To outline current approaches for managing candiduria.

Main Methods:

Literature review of studies on candiduria.
Analysis of factors influencing candiduria prevalence and management.
Discussion of diagnostic and therapeutic considerations.

Main Results:

Candiduria is caused by Candida species, including Candida albicans and Candida glabrata.
Clear definitions for fungal urinary tract infections and robust clinical trials are lacking.
Catheter removal, obstruction/stone evaluation, and post-void residual assessment are crucial management steps.

Conclusions:

While optimal management is unknown, interventions like catheter removal are beneficial.
High-risk patients or those with persistent candiduria may benefit from Amphotericin B bladder irrigants or oral fluconazole.