Management of candiduria

Area of Science:

• Infectious Diseases
• Mycology
• Urology

Background:

• Candiduria, a fungal urinary tract infection, is increasingly prevalent.
• Factors contributing to its rise include broad-spectrum antibacterial use and immunosuppression.
• The optimal management strategy for candiduria is not well-defined.

Purpose of the Study:

• To review the current understanding and management of candiduria.
• To highlight challenges in defining and treating fungal urinary tract infections.
• To outline current approaches for managing candiduria.

Main Methods:

• Literature review of studies on candiduria.
• Analysis of factors influencing candiduria prevalence and management.
• Discussion of diagnostic and therapeutic considerations.

Main Results:

• Candiduria is caused by Candida species, including Candida albicans and Candida glabrata.
• Clear definitions for fungal urinary tract infections and robust clinical trials are lacking.
• Catheter removal, obstruction/stone evaluation, and post-void residual assessment are crucial management steps.

Conclusions:

• While optimal management is unknown, interventions like catheter removal are beneficial.
• High-risk patients or those with persistent candiduria may benefit from Amphotericin B bladder irrigants or oral fluconazole.