Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Routes of Drug Administration: Parenteral

Routes of Drug Administration: Parenteral

The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...

Pneumonia IV: Management

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Outcomes of a trial of HIV-1 immunogen in patients with HIV infection.

JAMA·2001

Same author

Outpatient management of infectious diseases.

International journal of clinical practice. Supplement·2001

Same author

Editorial response: direct involvement of physicians is vital to outpatient parenteral antimicrobial therapy for central nervous system infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·1999

Same author

Evolution of outpatient parenteral antibiotic therapy.

Infectious disease clinics of North America·1999

Same author

Outpatient use of intravenous antibiotics. Introduction.

The American journal of medicine·1994

Same author

Treatment of skin and soft-tissue infections utilizing an outpatient parenteral drug delivery device: a multicenter trial. HIAT Study Group.

The American journal of medicine·1994

Search research articles

Related Experiment Video

Updated: Jul 3, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

Outpatient parenteral antibiotic therapy.

¹Infectious Diseases, Infectious Diseases Physicians Inc., Fairfax Hospital, 3289 Woodburn Road, Suite 200, Annandale, VA 22003, USA.

International Journal of Antimicrobial Agents

|January 1, 1995

Summary

Outpatient parenteral antibiotic therapy (OPAT) is a safe and effective treatment option for various infections. Its success relies on careful management and coordination among healthcare professionals, making it a practical choice for patients.

More Related Videos

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Related Experiment Videos

Last Updated: Jul 3, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Area of Science:

Infectious Diseases
Pharmacology
Healthcare Management

Background:

Parenteral antibiotic administration in outpatient settings is clinically validated as safe, cost-effective, and practical.
Advancements in antibiotic development, including drugs with extended half-lives like ceftriaxone and cefotetan, have significantly enabled outpatient parenteral antibiotic therapy (OPAT).

Purpose of the Study:

To highlight the feasibility and benefits of outpatient parenteral antibiotic therapy (OPAT).
To underscore the essential components for successful OPAT implementation and management.

Main Methods:

Review of clinical studies and established practices in antibiotic therapy.
Analysis of factors contributing to the efficacy and practicality of OPAT.
Identification of key stakeholders and management strategies for OPAT.

Main Results:

OPAT demonstrates safety, cost-effectiveness, and practicality in clinical settings.
Newer antibiotics with prolonged half-lives enhance the viability of OPAT.
Effective OPAT requires multidisciplinary collaboration and clear guidelines.

Conclusions:

Outpatient parenteral antibiotic therapy (OPAT) is a viable and beneficial treatment modality for a range of infections.
Successful OPAT hinges on coordinated care among physicians, nurses, pharmacists, and administrators.
Conditions such as osteomyelitis, soft tissue infections, chronic UTIs, and ENT infections are suitable for OPAT treatment.