Outpatient parenteral antibiotic therapy
1Infectious Diseases, Infectious Diseases Physicians Inc., Fairfax Hospital, 3289 Woodburn Road, Suite 200, Annandale, VA 22003, USA.
Abstract:
Clinical studies have shown that outpatient administration of parenteral antibiotics is sage, cost-effective and practical. The development of new antibiotics with prolonged half-lives, such as ceftriaxone or cefotetan, has facilitated outpatient parenteral antibiotic therapy (OPAT). Good OPAT management requires coordination of physicians, nurses, pharmacists and health care administrators, and the establishment of firm guidelines. A variety of infections can be treated through OPAT, including osteomyelitis and soft tissue infections, chronic urinary tract infections, and ear, nose and throat infections.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Routes of Drug Administration: Parenteral
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

