Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Gallbladder

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...

Diseases of the Liver and Gallbladder

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

Cholecystitis

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

Glucose Transporters

Glucose Transporters

Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Inborn Errors of Metabolism

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Low-level parental mosaicism in an apparent de novo case of Peutz-Jeghers syndrome.

Familial cancer·2018

Same author

Two-year audit of a nurse-supervised leg ulcer clinic in a district general hospital.

Journal of wound care·2016

Same author

Case report: metachronous central nervous system desmoid tumours and thyroid carcinoma in a young familial adenomatous polyposis patient.

Familial cancer·2013

Same author

Repeat surgery following breast conservation and intra-operative sentinel lymph node analysis for breast cancer.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2013

Same author

The axillary nodal harvest in breast cancer surgery is unchanged by sentinel node biopsy or the timing of surgery.

International journal of breast cancer·2012

Same author

The effect of introducing an in-theatre intra-operative specimen radiography (IOSR) system on the management of palpable breast cancer within a single unit.

Breast (Edinburgh, Scotland)·2011

Search research articles

Related Experiment Video

Updated: Jul 3, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Gall-bladder agenesis and associated anomalies.

C Yiangou¹, B Shorey, A D Spigelman

¹Department of Surgery, Central Middlesex Hospital, London NW10.

HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery

|January 1, 1995

Summary

This summary is machine-generated.

Congenital absence of the gall-bladder (agenesis) is rare and often linked to other birth defects. Early diagnosis is crucial, as ultrasound may be inconclusive, requiring further noninvasive tests to avoid unnecessary surgery.

Related Experiment Videos

Last Updated: Jul 3, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Area of Science:

Gastroenterology
Medical Imaging
Pediatric Surgery

Background:

Congenital absence of the gall-bladder, or agenesis, is a rare condition.
It is frequently associated with other congenital anomalies, particularly skeletal and cardiovascular defects.
Diagnosis can be challenging, with ultrasound often proving inconclusive.

Purpose of the Study:

To report two cases of gall-bladder agenesis diagnosed during laparoscopy.
To highlight the association with other congenital anomalies.
To emphasize the diagnostic challenges and the need for appropriate investigations.

Main Methods:

Case report of two patients with diagnosed gall-bladder agenesis.
Review of patient history for associated congenital defects.
Discussion of diagnostic modalities, including ultrasound and noninvasive tests.

Main Results:

Two cases of gall-bladder agenesis were identified during laparoscopy.
Both patients presented with a history of skeletal and cardiovascular anomalies.
The diagnostic process for gall-bladder agenesis can be difficult, with ultrasound often being inconclusive.

Conclusions:

Gall-bladder agenesis is a rare condition often accompanied by other congenital defects.
The presence of skeletal and cardiovascular anomalies should raise suspicion for gall-bladder agenesis.
Further noninvasive investigations are essential to confirm the diagnosis and prevent unnecessary surgical interventions.