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Updated: Jul 3, 2026

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
Published on: November 7, 2018
Hepatitis B viral genotype in Taiwanese patients with acute hepatitis B
Yi-Wen Huang1, Chih-Lin Lin, Pei-Jer Chen
1Liver Unit, Department of Internal Medicine, Cathay General Hospital, Taipei, Taiwan.
Background/Aims:
The correlation of HBV genotype with clinical outcome has been recognized in chronic hepatitis B patients. However, there are few reports on the distribution and clinical significance of HBV genotypes in acute hepatitis B patients.
Methodology:
Nineteen acute hepatitis B patients were identified and their HBV genotypes were determined. The serological and clinical data were thus compared between patients with different HBV genotypes.
Results:
Two HBV genotypes (B and C) were found in the patients. Genotype B was more predominant than genotype C (12 vs. 7). The age, serum alanine aminotransferase level, serum alpha-fetoprotein level, and serum HBV DNA level were not significantly different between patients infected with genotype B or C. None of them had persistent HBsAg for longer than 6 months.
Conclusions:
Genotype B predominates in acute hepatitis B patients in Taiwan; however, the clinical features between genotype B and genotype C patients are comparable.
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