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Related Experiment Video

Updated: Jul 3, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection

Published on: June 24, 2025

Biofilms in nephrology.

Richard J Marcus¹, J Christopher Post, Paul Stoodley

¹Division of Nephrology & Hypertension, Allegheny General Hospital, Pittsburgh, PA 15212, USA. rmarcus@wpahs.org

Expert Opinion on Biological Therapy

|July 11, 2008

Summary

Biofilms, bacterial communities, are common in nephrology, contributing to kidney stones and infections. Strategies to combat these resilient biofilms in clinical settings are discussed.

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Development of a Polymicrobial Colony Biofilm Model to Test Antimicrobials in Cystic Fibrosis

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Published on: September 20, 2024

Area of Science:

Microbiology
Nephrology
Infectious Diseases

Background:

Biofilms are prevalent bacterial communities found in moist environments.
Biofilm formation is implicated in the development and persistence of infectious diseases.
In nephrology, biofilms contribute to kidney stones, dialysis equipment issues, and persistent renal/urinary tract infections.

Purpose of the Study:

To elucidate biofilm physiology.
To examine the impact of biofilms on infectious diseases.
To focus on biofilms' role in kidney stones, catheters, and dialysis.

Main Methods:

Conducted a Medline literature search.
Included English language articles published up to early 2008.
Utilized keywords: biofilm, nephrology, renal, calculi, infection.

Main Results:

Biofilms are ubiquitous in clinical nephrology.
Biofilms play a role in the pathogenesis of resistant infections.
Strategies for mitigating biofilm effects in nephrology were identified.

Conclusions:

Biofilms are a significant factor in nephrology practice.
Understanding biofilm mechanisms is crucial for treating resistant infections.
Effective strategies exist to reduce biofilm-related complications in nephrology.