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Biogas Purification through the use of a Microalgae-Bacterial System in Semi-Industrial High Rate Algal Ponds
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Optimization of an industrial microalgae fermentation.

A K Hilaly1, M N Karim, D Guyre

  • 1Colorado State University, Department of Agricultural and Chemical Engineering, Fort Collins, Colorado 80523.

Biotechnology and Bioengineering
|February 20, 1994
PubMed
Summary
This summary is machine-generated.

This study optimized microalgae fermentation for industrial applications. A direct search algorithm proved simplest and most effective for maximizing cellular productivity.

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Area of Science:

  • Biotechnology
  • Biochemical Engineering
  • Industrial Microbiology

Background:

  • Industrial microalgae fermentation requires optimization for enhanced cellular productivity.
  • Pilot plant data from Coors Biotech Products Company provided the basis for mathematical modeling.

Purpose of the Study:

  • To investigate and optimize cellular productivity in industrial microalgae fermentation.
  • To develop and compare mathematical models and control algorithms for fermentation optimization.

Main Methods:

  • Development of a mathematical model based on pilot plant data.
  • Application of Pontryagin's maximum principle for optimal feed policy determination.
  • Implementation of feedback control algorithms, adaptive optimization (steepest descent, recursive least squares), and a direct search algorithm for optimization.

Main Results:

  • The direct search algorithm was identified as the preferable optimization scheme due to its simplicity.
  • Experimental results from real-time feedback algorithm application showed good agreement with theoretical analyses.
  • Adaptive optimization determined the optimum dilution rate during continuous operation.

Conclusions:

  • The direct search algorithm offers a practical and effective method for optimizing industrial microalgae fermentation.
  • Mathematical modeling and feedback control are valuable tools for enhancing cellular productivity.
  • The study successfully demonstrated the feasibility of optimizing microalgae fermentation processes using advanced control strategies.