A prototype neural network supervised control system for Bacillus thuringiensis fermentations
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Updated: Jul 3, 2026

Single-cell Microfluidic Analysis of Bacillus subtilis
Published on: January 26, 2018
Q Zhang1, J F Reid, J Bruce Litchfield
1Department of Agricultural Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Abstract:
This article discusses the development of a prototype neural network-based supervisory control system for Bacillus thuringiensis fermentations. The input pattern to the neural network included the type of inoculum, operation temperature, pH value, accumulated process time, optical density in fermentation medium, and change in optical density. The output from the neural network was the predicted optical density for the next sampling time. The control system has been implemented in both a computer simulation and a laboratory fermentation experiment with promising results. (c) 1994 John Wiley & Sons, Inc.
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