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Related Concept Videos

Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...

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Related Experiment Video

Updated: Jul 3, 2026

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
10:45

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Published on: May 31, 2017

Review: Tissue engineering in the nervous system.

R Bellamkonda1, P Aebischer

  • 1Division of Surgical Research, Pavillon 3, Lausanne University Medical School, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.

Biotechnology and Bioengineering
|March 25, 1994
PubMed
Summary
This summary is machine-generated.

Tissue engineering is making nervous system repair possible by addressing neurochemical and neuroanatomical complexities. This review covers solutions for neural component replacement, tissue regeneration, and novel neural biosensors.

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Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering
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Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

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Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Tissue Engineering

Background:

  • Nervous system complexity poses significant challenges for tissue engineering.
  • Understanding neurochemical and neuroanatomical architecture is crucial for neural repair.
  • Advances in molecular neurobiology, gene transfer, and biomaterials engineering are enabling neural tissue engineering.

Purpose of the Study:

  • To review engineered solutions for nervous system repair and regeneration.
  • To explore applications in functional replacement of neuroactive components.
  • To discuss the development of neural cell-based biosensors and in vitro neural circuits.

Main Methods:

  • Review of engineered solutions for neural tissue engineering challenges.
  • Focus on functional replacement, tissue regeneration, and biosensor development.
  • Integration of molecular neurobiology, gene transfer, and biomaterials science.

Main Results:

  • Engineered solutions address functional replacement of neuroactive components.
  • Strategies are presented for rescuing or regenerating degenerated neural tissue.
  • Development of intelligent neural cell-based biosensors and simple in vitro neural circuits is discussed.

Conclusions:

  • Tissue engineering offers promising solutions for nervous system repair.
  • Interdisciplinary approaches combining biology and engineering are key.
  • Future applications include neural regeneration and advanced neural biosensors.