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Related Experiment Video

Updated: Jul 3, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
05:16

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

Indirect pulp therapy and stepwise excavation.

Lars Bjørndal1

  • 1Department of Cariology and Endodontics, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Denmark. lb@odont.ku.dk

Pediatric Dentistry
|July 12, 2008
PubMed
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Optimal randomized clinical studies are lacking for deep carious lesions. Current evidence suggests stepwise excavation and indirect pulp treatment avoid pulp exposure, but the best approach remains unclear.

Area of Science:

  • Dentistry
  • Cariology
  • Endodontics

Background:

  • Deep carious lesions present a treatment dilemma with a lack of high-quality evidence.
  • Existing systematic reviews highlight the scarcity of optimal randomized clinical studies.
  • Current observational data suggest indirect pulp treatment and stepwise excavation are viable options to prevent pulp exposure.

Purpose of the Study:

  • To review current treatment concepts for deep carious lesions.
  • To evaluate the evidence from systematic reviews and observational studies.
  • To introduce a modified stepwise excavation approach and highlight ongoing research.

Main Methods:

  • Systematic review of existing literature on deep carious lesion treatments.
  • Analysis of observational studies on indirect pulp treatment and stepwise excavation.

Related Experiment Videos

Last Updated: Jul 3, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
05:16

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

  • Description of a modified stepwise excavation technique.
  • Mention of the ongoing Caries and Pulp (CAP) trial, a multi-center randomized clinical trial.

    • Main Results:

    • Systematic reviews conclude that optimal randomized clinical studies are lacking.
    • Observational studies indicate that both indirect pulp treatment and stepwise excavation can avoid pulp exposure.
    • The optimal treatment approach for deep carious lesions is not yet definitively established.
    • A modified stepwise excavation aims to arrest caries progression with less invasive intervention.

    Conclusions:

    • There is a critical need for high-quality randomized clinical trials to determine the best treatment for deep carious lesions.
    • Stepwise excavation and indirect pulp treatment are promising conservative approaches.
    • Ongoing trials like the CAP trial are crucial for advancing treatment guidelines.