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Hearing01:31

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
Perception of Sound Waves01:01

Perception of Sound Waves

The human ear is not equally sensitive to all frequencies in the audible range. It may perceive sound waves with the same pressure but different frequencies as having different loudness. Moreover, the perception of sound waves depends on the health of an individual's ears, which decays with age. The health of one's ears may also be affected by regular exposure to loud noises.
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same frequency...
Heart Sounds01:15

Heart Sounds

Heart sounds are generated by the turbulence in blood flow due to the closing of heart valves. These sounds are best perceived slightly away from the valves, where the blood flow disseminates the sound.
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V) valves at the...
Sound Intensity Level00:53

Sound Intensity Level

Humans perceive sound by hearing. The human ear helps sound waves reach the brain, which then interprets the waves and creates the perception of hearing. The loudness of the environment in which a person is located determines whether they can distinguish between different sound sources.
The human ear can perceive an extensive range of sound intensity, necessitating the use of the logarithmic scale to define a physical quantity—the intensity level. It is a ratio of two intensities and hence a...
Sound as Pressure Waves01:17

Sound as Pressure Waves

Sound waves, which are longitudinal waves, can be modeled as the displacement amplitude varying as a function of the spatial and temporal coordinates. As a column of the medium is displaced, its successive columns are also displaced. As the successive displacements differ relatively, a pressure difference with the surrounding pressure is created. The gauge pressure varies across the medium.
The pressure fluctuation depends on the difference in displacements between the successive points in the...
The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.

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Related Experiment Video

Updated: Jul 3, 2026

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
07:05

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training

Published on: August 24, 2017

Tinnitus treatment with customized sounds.

Jaime A Pineda1, F Richard Moore, Erik Viirre

  • 1Department of Cognitive Science University of California, San Diego, La Jolla, California 92093, USA.

The International Tinnitus Journal
|July 12, 2008
PubMed
Summary
This summary is machine-generated.

Customized sound therapy (CST) effectively reduces tinnitus by targeting abnormal brain activity. This innovative approach offers rapid, safe relief and improves hearing metrics within weeks.

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Area of Science:

  • Neuroscience
  • Auditory Neuroscience
  • Clinical Audiology

Background:

  • Tinnitus pathophysiology is increasingly linked to abnormal central auditory system activity, not peripheral issues.
  • Tinnitus can cause maladaptive tonotopic map reorganization in the auditory cortex.
  • This cortical reorganization may be reversible through targeted neural plasticity interventions.

Purpose of the Study:

  • To investigate the efficacy of customized sound therapy (CST) in ameliorating tinnitus symptoms.
  • To explore CST's potential to reverse central auditory dysfunction and cortical reorganization associated with tinnitus.
  • To evaluate the safety and speed of tinnitus reduction using CST.

Main Methods:

  • Utilized customized sounds designed to match individual tinnitus subjective experiences.
  • Administered CST to participants with tinnitus over a 3-week period.
  • Assessed tinnitus severity using the Tinnitus Handicap Questionnaire and measured changes in hearing thresholds and auditory N100 intensity dependence.

Main Results:

  • CST demonstrated rapid and safe tinnitus reduction, with participants reporting immediate relief.
  • Significant improvements were observed in Tinnitus Handicap Questionnaire scores and hearing thresholds within 3 weeks.
  • Changes in auditory N100 intensity dependence indicated a reversal of tinnitus-related cortical reorganization, normalizing responses to tinnitus pitch.

Conclusions:

  • CST is a promising therapeutic approach for tinnitus, effectively addressing central auditory dysfunction.
  • The therapy's ability to reverse maladaptive cortical changes suggests a novel mechanism for tinnitus management.
  • Preliminary findings support CST as a quick, safe, and effective intervention for tinnitus relief and auditory function improvement.