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Related Concept Videos

Jaundice01:25

Jaundice

Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...
Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

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Isolation of Neonatal Extrahepatic Cholangiocytes
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Does circumcision increase neonatal jaundice?

E Eroğlu1, S Balci, Hc Ozkan

  • 1Section of Pediatric Surgery, VKF American Hospital, Istanbul, Turkey. egemene@amerikanhastanesi.com.tr

Acta Paediatrica (Oslo, Norway : 1992)
|July 12, 2008
PubMed
Summary
This summary is machine-generated.

Newborn circumcision on the second day of life is safe and does not impact feeding frequency, bowel movements, or serum bilirubin levels. This procedure does not increase the risk of neonatal jaundice in healthy newborns.

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Area of Science:

  • Neonatal care
  • Pediatric surgery

Background:

  • Neonatal circumcision is a common procedure.
  • Concerns exist regarding its potential impact on infant physiology.

Purpose of the Study:

  • To assess the effects of early newborn circumcision on feeding frequency.
  • To evaluate the impact of circumcision on serum bilirubin levels.

Main Methods:

  • A comparative study of 60 male newborns, with 30 circumcised.
  • Inclusion criteria: 35-40 weeks gestation, weight >3000g, no antenatal/perinatal issues.
  • Monitored weight, feeding frequency, urination, stooling, and serum bilirubin levels.

Main Results:

  • No statistically significant differences were observed between the circumcised and control groups.
  • Circumcision did not affect feeding frequency or bowel movements on day 3.
  • Serum bilirubin levels on day 4 were not significantly increased by circumcision.

Conclusions:

  • Newborn circumcision, when performed by experienced practitioners on the second day of life, is safe.
  • The procedure does not adversely affect feeding, elimination, or increase the risk of neonatal jaundice.
  • Early newborn circumcision is a safe practice with no significant physiological impact on healthy infants.