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Updated: Jul 3, 2026
10:34
Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Published on: August 30, 2020
Nonaneurysmal nonperimesencephalic subarachnoid hemorrhage: is it a benign entity?
Sunil K Gupta1, Rahul Gupta, Virender K Khosla
1Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh-160012, India. drguptasunil@gmail.com
Surgical Neurology
|July 12, 2008
Summary
Patients with nonaneurysmal perimesencephalic non-aneurysmal subarachnoid hemorrhage (n-PMN SAH) have a good prognosis and benign clinical course. A second DSA is crucial to rule out aneurysms and vascular lesions.
Area of Science:
- Neurology
- Neurosurgery
- Radiology
Background:
- Limited data exists on nonaneurysmal perimesencephalic non-aneurysmal subarachnoid hemorrhage (n-PMN SAH).
- This study analyzes and compares clinical characteristics of n-PMN SAH with PMN SAH and aneurysmal SAH.
Purpose of the Study:
- To analyze the clinical characteristics of n-PMN SAH.
- To compare n-PMN SAH with PMN SAH and aneurysmal SAH.
- To evaluate the outcomes of patients with n-PMN SAH.
Main Methods:
- Patients with spontaneous SAH and negative initial DSA/CTA underwent repeat imaging.
- A second DSA was performed 4-6 weeks later if initial results were negative.
- Patients were classified into PMN SAH and n-PMN SAH groups if no aneurysm was found after two investigations.
Main Results:
- Out of 61 patients with negative initial imaging, 18 had PMN SAH and 34 had n-PMN SAH after exclusions.
- No mortality was observed in the PMN SAH and n-PMN SAH groups.
- At 1.8 years follow-up, 100% of PMN SAH and 94.1% of n-PMN SAH patients had a good outcome.
Conclusions:
- n-PMN SAH patients have a good prognosis and benign clinical course, similar to PMN SAH.
- A second DSA is essential to exclude aneurysms or other vascular lesions.
- Associated comorbid illnesses were more frequent in PMN SAH and n-PMN SAH compared to aneurysmal SAH.
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