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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

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Foveolitis associated with dengue Fever: a case series

Boon-Kwang Loh1, Kristine Bacsal, Soon-Phaik Chee

  • 1Singapore National Eye Centre, Singapore. lohboonkwang@yahoo.com

Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
|July 12, 2008
PubMed
Abstract

Insights

Foveolitis, a novel finding in dengue fever (DF), presents as a yellow-orange lesion at the fovea. Optical coherence tomography (OCT) aids in diagnosing this condition, which may impact visual acuity.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Retinal Imaging

Background:

  • Dengue fever (DF) is a common viral infection with varied symptoms.
  • Ocular manifestations of DF are rare, with foveal involvement previously undescribed.
  • This study introduces DF-associated foveolitis.

Purpose of the Study:

  • To describe the clinical features of foveolitis in patients with dengue fever.
  • To investigate the role of optical coherence tomography (OCT) in diagnosing and monitoring this condition.

Main Methods:

  • Retrospective review of patients with DF-associated maculopathy.
  • Analysis of patients with foveal yellow-orange lesions and outer neurosensory retina disruption on OCT.
  • Assessment of visual acuity and electroretinography responses.

Main Results:

  • Ten eyes of 6 patients with DF-associated foveolitis were analyzed.
  • A characteristic yellow-orange foveal lesion and outer neurosensory retina disruption on OCT were observed.
  • Reduced visual acuity and decreased foveal/parafoveal responses on multifocal electroretinography were noted.

Conclusions:

  • Foveolitis can be associated with dengue fever.
  • OCT is a valuable diagnostic and monitoring tool for DF-associated foveolitis.
  • Treatment strategies for DF-associated foveolitis vary based on visual acuity.

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