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Updated: Jul 3, 2026
Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors
Published on: December 20, 2024
[The solid pseudopapillary tumor (SPT)--a rare neoplasm of the pancreas]
1Abteilung für Transplantationschirurgie, Chirurgie von Leber, Gallenwegen und Pankreas, Klinikum der Johannes-Gutenberg-Universität Mainz, Mainz. foltys@transplantation.klinik.uni-mainz.de
Background:
In general, the rare SPT is a tumour of low malignancy predominantly affecting young women. The outcome after radical resection is favourable. In exceptional cases the tumour presents as solid pseudopapillary carcinoma (SPC) with typical malignant features and even metastases. Unresectable liver metastases can be treated with RFA, TACE or chemotherapy.
Methods:
We retrospectively reviewed the surgical approach, immunohistochemistry and clinical outcome in five female patients (1998--2007).
Results:
The mean age was 16 years (range: 13-47 years). For radical tumour removal a pancreato-duodenectomy (n = 3), a distal pancreatectomy (n = 1) and an enucleation (n = 1) were performed. We encountered a mean tumour diameter of 8 cm (range: 6-15 cm), an angioinvasion (3/5) and a lymphatic infiltration (1/5). After 30 to 101 months follow-up four patients were free of recurrence. Chemotherapy has resulted in a survival of over 98 months in a case of SPC with liver metastases.
Conclusion:
SPT is a tumour of low malignancy. Radical resection is recommended for long-term recurrence-free survival. Chemotherapy may prolong survival in SPC with unresectable metastases.
