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Chronic Bowel Disorders: Introduction

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Updated: Jul 3, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

[Behçet's disease].

H S Brand1, F F van Beusichem, A van Nieuw Amerongen

  • 1AfdelingTandheelkundige Basiswetenschappen, sectie Orale Biochemie, Academisch Centrum Tandheelkunde Amsterdam (ACTA). hs.brand@vumc.nl

Nederlands Tijdschrift Voor Tandheelkunde
|July 16, 2008
PubMed
Summary
This summary is machine-generated.

Behçet

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Last Updated: Jul 3, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Area of Science:

  • Rheumatology
  • Immunology
  • Oral Medicine

Context:

  • Behçet's disease is a chronic, multisystem inflammatory disorder.
  • Characterized by recurrent oral/genital ulcers, uveitis, skin lesions, vasculitis, and arthritis.
  • Oral manifestations are nearly universal, impacting 98% of patients.

Purpose:

  • To summarize the clinical characteristics and management of Behçet's disease.
  • To highlight the high prevalence of oral health issues in Behçet's patients.
  • To outline current therapeutic strategies for managing disease symptoms.

Summary:

  • Behçet's disease presents with diverse systemic manifestations, notably recurrent oral ulcers.
  • Patients with Behçet's disease exhibit increased prevalence of plaque, periodontal disease, and potentially caries.
  • Symptomatic treatment is key, with medications including colchicine, corticosteroids, and immunosuppressives.

Impact:

  • Emphasizes the critical role of comprehensive oral health care in managing Behçet's disease.
  • Informs clinicians about the increased oral health burden in these patients.
  • Provides an overview of available pharmacological interventions for symptom control.