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Published on: June 12, 2021
[Study on the effect of Part III from Cynomorium songaricum on immunosuppressive mice induced by cyclophosphamide]
Ru-Xue Zhang1, Zheng-Ping Jia, Mao-Xing Li
1Lanzhou General Hospital, Lanzhou Command of PLA, Lanzhou 730050, China. empriqqq@public.lz.gs.cn
Objective:
To study the immunomodulatory effect of Part III of Cynomorium songaricum Rupr. on the immunosuppressive mice.
Methods:
The immunity-deficiency model was induced by intraperitoneal injection of cyclophosphamide (CTX) at the dose of 100 mg/kg in mice; all the animals were divided into normal control group, immunity-deficiency model group, Part III treated group (300 mg/kg) and positive control group (TSPG, 300 mg/kg). The hemogram of peripheral blood, the index of immune organs, the phagocytosis activity of macrophage, the content of serum hemolysin were measured.
Results:
The index of organs, the phagocytosis activity of macrophage and the content of serum hemolysin in the model group increased after administrated of Part III.
Conclusion:
Part III from Cynomorium songaricum Rupr. has protective effect on the immunosuppressive mice, which may be related to the increasing of humoral immunity and nonspecific immunity.
