Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jul 3, 2026

Early Weight-Bearing Rehabilitation Protocol After Anterior Cruciate Ligament Reconstruction

Early Weight-Bearing Rehabilitation Protocol After Anterior Cruciate Ligament Reconstruction

Published on: March 1, 2024

How to quantify knee function after total knee arthroplasty?

M C Boonstra¹, M C De Waal Malefijt, N Verdonschot

¹Orthopaedic Research Lab, Radboud University Nijmegen Medical Centre, The Netherlands.

|July 16, 2008

Summary

Quantitative functional knee tests are crucial for monitoring increasing demands after total knee arthroplasty (TKA). The sit-to-stand and timed-up-and-go tests effectively measure knee function, proving selective and valid for patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The intact meniscus and an artificial meniscus prosthesis both act as a shock absorber in the knee joint.

The Knee·2026

Same author

Exploring healthy knee kinematic phenotypes obtained through dynamic CT imaging: A cluster analysis study.

Journal of biomechanics·2024

Same author

The first-generation anatomical medial meniscus prosthesis led to unsatisfactory results: a first-in-human study.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2022

Same author

The sensitivity of an anatomical coordinate system to anatomical variation and its effect on the description of knee kinematics as obtained from dynamic CT imaging.

Medical engineering & physics·2022

Same author

The importance of continuous remnant preservation in anterior cruciate ligament reconstruction.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2021

Same author

Biomechanical loading of the porcine femorotibial joint during maximal movements: An exploratory, ex vivo study.

Veterinary journal (London, England : 1997)·2020

Area of Science:

Orthopedics and Rehabilitation Science
Biomechanical Engineering
Clinical Assessment Tools

Background:

Total knee arthroplasty (TKA) is increasingly performed in younger, more active populations.
Rising functional demands necessitate reliable quantitative assessments of knee function post-TKA.
Existing assessment tools require evaluation for selectivity and content validity, particularly independence from pain.

Purpose of the Study:

To identify quantitative functional knee tests that are selective and content valid for assessing knee function after TKA.
To compare patient-reported outcomes (WOMAC, Knee Society score) with performance-based tests (sit-to-stand, maximal isometric contraction, timed-up-and-go).
To determine which tests can effectively discriminate between TKA patients and healthy controls and are pain-independent.

Related Experiment Videos

Last Updated: Jul 3, 2026

Early Weight-Bearing Rehabilitation Protocol After Anterior Cruciate Ligament Reconstruction

Early Weight-Bearing Rehabilitation Protocol After Anterior Cruciate Ligament Reconstruction

Published on: March 1, 2024

Main Methods:

A cohort of 28 patients 16 months post-TKA was compared to 31 healthy control subjects.
Evaluated patient-based questionnaires (WOMAC, Knee Society score).
Assessed performance-based tests: sit-to-stand movement, maximal isometric contraction, and timed-up-and-go.

Main Results:

The sit-to-stand movement test demonstrated selectivity and functional content validity.
The timed-up-and-go test was also found to be selective and functionally content valid.
Both tests proved capable of discriminating between TKA patients and healthy controls and were relatively independent of pain.

Conclusions:

The sit-to-stand movement and timed-up-and-go tests are valuable, selective, and content-valid tools for assessing knee function post-TKA.
Timed-up-and-go offers a quick global function assessment, while sit-to-stand provides biomechanical insights into knee function.
These performance-based tests are recommended for monitoring functional recovery and demands in the TKA population.