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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

Depression, anxiety, and neuropsychological performance in coronary artery bypass graft patients: a follow-up study

Nathalie Stroobant1, Guy Vingerhoets

  • 1University Hospital, Ghent, Laboratory for Neuropsychology, 4K3, De Pintelaan 185, B-9000, Ghent, Belgium. Nathalie.Stroobant@UGent.be

Psychosomatics
|July 16, 2008
PubMed

Insights

Coronary-artery bypass surgery (CABG) can impact mood. Some patients experience lasting depression, especially those with pre-operative symptoms, while anxiety typically decreases post-surgery.

Area of Science:

  • Cardiology
  • Psychiatry
  • Neuropsychology

Background:

  • Coronary-artery bypass surgery (CABG) is a major life event with significant psycho-emotional effects.
  • Patient and family well-being are impacted by the surgical experience.

Purpose of the Study:

  • To investigate the incidence and progression of depression and anxiety in patients.
  • To examine the long-term relationship between mood disorders and neuropsychological deficits after CABG.

Main Methods:

  • Prospective study of 53 patients undergoing CABG.
  • Mood and neuropsychological assessments were conducted pre-surgery and at 6 days, 6 months, and 3-5 years post-surgery.

Main Results:

  • One-third of patients exhibited mild-to-moderate depressive symptoms pre-surgery.
  • Post-surgery, one-fourth of patients still had elevated depression scores, but anxiety decreased significantly.
  • Pre-operative depression severity correlated with sustained post-operative depressive symptoms.
  • Visuomotor performance was most affected by mood disturbances.

Conclusions:

  • Patients with moderate pre-operative depression are at risk for persistent depression up to 5 years after CABG.
  • Early identification and management of pre-operative depression are crucial for long-term patient outcomes.
Abstract

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