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Published on: August 7, 2017
Exposure to indoor mould and children's respiratory health in the PATY study
T Antova1, S Pattenden, B Brunekreef
1Environmental Health Unit, NCPHP, Sofia, Bulgaria.
Insights
Living in a damp home with visible mould is linked to poorer respiratory health in children. This study analyzed data from over 58,000 children, confirming mould as a significant risk factor for cough and other respiratory issues.
Area of Science:
- Environmental health
- Pediatric respiratory medicine
- Epidemiology
Background:
- Damp and mouldy homes are suspected to negatively impact children's respiratory health.
- Public perception may underestimate mould as a significant health risk.
- The study utilizes data from the Pollution and the Young (PATY) study, pooling information from 12 cross-sectional studies.
Purpose of the Study:
- To assess the association between indoor mould exposure and a range of respiratory and allergic symptoms in children.
- To investigate the impact of air quality on pediatric respiratory disorders.
- To quantify the risk of respiratory symptoms associated with visible household mould.
Main Methods:
- Data from over 58,000 children aged 6-12 years were pooled from 12 cross-sectional studies across Russia, North America, and Europe.
- Logistic regression models were employed to estimate associations between reported household mould and eight respiratory/allergic symptoms, controlling for individual and area-level factors.
- Meta-analysis was used to estimate mean effects and assess heterogeneity between study-specific results.
Main Results:
- Visible mould was reported by 13.9% in Russia to 39.1% in North America.
- Consistent positive associations were found between mould exposure and children's respiratory symptoms, including nocturnal cough (OR 1.30) and morning cough (OR 1.50).
- Stronger effects of mould were observed in more crowded households for asthma and sensitivity to inhaled allergens, but no consistent interactions with age, sex, or parental smoking were detected.
Conclusions:
- Indoor mould exposure is consistently linked to adverse respiratory health outcomes in children.
- The findings highlight the importance of addressing mould in homes to protect pediatric respiratory health.
- This large-scale international study provides robust evidence on the detrimental effects of indoor mould on children's well-being.
Background:
Living in a damp or mouldy home reportedly damages children's respiratory health, yet mould appears not to be a prominent risk factor in the public's perception. Analyses of data on over 58,000 children from the Pollution and the Young (PATY) study are presented. In this collaboration, researchers from 12 cross-sectional studies pooled their data to assess the effects of air quality on a spectrum of children's respiratory disorders.
Method:
Original studies were conducted in Russia, North America and 10 countries in Eastern and Western Europe. Pooled analyses were restricted to children aged 6-12 years. Associations between visible mould reported in the household and a spectrum of eight respiratory and allergic symptoms were estimated within each study. Logistic regressions were used, controlling for individual risk factors and for study area. Heterogeneity between study-specific results and mean effects (allowing for heterogeneity) were estimated using meta-analysis.
Results:
Visible mould was reported by 13.9% of respondents in Russia, increasing to 39.1% in North America. Positive associations between exposure to mould and children's respiratory health were seen with considerable consistency across studies and across outcomes. Confounder-adjusted combined ORs ranged from 1.30 (95% CI 1.22 to 1.39) for "nocturnal cough" to 1.50 (1.31 to 1.73) for "morning cough". Evidence of stronger effects in more crowded households was statistically significant for only asthma and sensitivity to inhaled allergens. No consistent interactions between mould and age, sex or parental smoking were found.
Conclusion:
Indoor mould exposure was consistently associated with adverse respiratory health outcomes in children living in these diverse countries.
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