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[Eosinophilic esophagitis in 29 pediatric patients]

Cristina Targa Ferreira1, Mário C Vieira, Sandra Maria Gonçalves Vieira

  • 1Instituto do Aparelho Digestivo, Porto Alegre, RS. cristinatarga@terra.com.br

Arquivos De Gastroenterologia
|July 16, 2008
PubMed

Insights

Eosinophilic esophagitis (EoE) in children presents with varied symptoms, often mimicking reflux. Diagnosis requires esophageal biopsy, and treatments like swallowed fluticasone or diet restriction show symptom improvement.

Area of Science:

  • Gastroenterology
  • Pediatric Medicine
  • Allergy Immunology

Context:

  • Eosinophilic esophagitis (EoE) is an emerging esophageal inflammatory condition.
  • EoE shares symptoms with gastroesophageal reflux disease, complicating diagnosis in children.
  • Understanding EoE's pediatric presentation is crucial for timely diagnosis and management.

Purpose:

  • To detail the clinical features, diagnostic methods, treatments, and outcomes of 29 pediatric eosinophilic esophagitis cases.
  • To characterize symptom presentation across different age groups in children with EoE.
  • To evaluate treatment efficacy and histological response in children with EoE.

Summary:

  • Twenty-nine children (22 boys) diagnosed with eosinophilic esophagitis (EoE) were analyzed.
  • Common symptoms included vomiting and abdominal pain; age-specific presentations varied.
  • Endoscopic findings ranged from normal to furrowing and papules; treatment with fluticasone or diet led to symptom remission and reduced eosinophil counts.

Impact:

  • Highlights the importance of considering EoE in children with refractory reflux-like symptoms.
  • Emphasizes the necessity of esophageal biopsies for accurate EoE diagnosis.
  • Demonstrates the effectiveness of swallowed fluticasone and dietary modifications in managing pediatric EoE.
Abstract

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