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Related Concept Videos

Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...

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Related Experiment Video

Updated: Jul 3, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
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Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Published on: April 19, 2024

[Therapeutic application of collateral ventilation in diffuse pulmonary emphysema: study protocol presentation].

Roberto Saad1, Vicente Dorgan Neto, Marcio Botter

  • 1Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brasil. rsaad@uol.com.br

Jornal Brasileiro De Pneumologia : Publicacao Oficial Da Sociedade Brasileira De Pneumologia E Tisilogia
|July 16, 2008
PubMed
Summary

This study protocol evaluates a novel surgical procedure for severe emphysema patients experiencing persistent respiratory failure. The technique aims to create new air passages, potentially offering an alternative to lung transplant.

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Thermal Preconditioning During Ex-vivo Lung Perfusion for the Rehabilitation of Damaged Lung Grafts before Transplantation
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Published on: October 31, 2025

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Last Updated: Jul 3, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
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Thermal Preconditioning During Ex-vivo Lung Perfusion for the Rehabilitation of Damaged Lung Grafts before Transplantation
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Thermal Preconditioning During Ex-vivo Lung Perfusion for the Rehabilitation of Damaged Lung Grafts before Transplantation

Published on: October 31, 2025

Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Biomedical Engineering

Context:

  • Diffuse lung emphysema significantly impacts patient quality of life, often persisting despite standard pulmonary rehabilitation.
  • Severe lung hyperinflation in emphysema patients leads to disabling dyspnea and respiratory failure.
  • Current treatment options for advanced emphysema are limited to lung transplant or lung volume reduction surgery.

Purpose:

  • To present a protocol for evaluating a new surgical procedure designed to alleviate air trapping in severe emphysema.
  • To assess the feasibility and potential benefits of a novel surgical technique for emphysema patients.
  • To explore an alternative therapeutic option for patients with diffuse pulmonary emphysema refractory to standard care.

Summary:

  • The proposed protocol involves evaluating ten patients with severe emphysema and persistent disabling dyspnea.
  • The surgical method aims to create alternative expiratory pathways by draining lung parenchyma, facilitating air release from alveoli.
  • Patient selection requires meeting specific inclusion criteria and providing informed consent, pending ethical approval.

Impact:

  • This research could establish a new, less invasive surgical treatment for diffuse pulmonary emphysema.
  • Successful outcomes may offer a viable alternative to lung transplantation or lung volume reduction surgery.
  • The protocol's feasibility assessment is crucial for future clinical application and patient benefit.