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Updated: Jul 3, 2026

LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation
Published on: January 24, 2025
Light sources for photodynamic inactivation of bacteria
Mihaela Antonina Calin1, S V Parasca
1National Institute of Research and Development for Optoelectronics, P.O. Box MG-5, 1 Atomistilor Street, 077125, Magurele, Ilfov, Romania. micalin@inoe.inoe.ro
Abstract:
Bacteria have an important role in human and animal morbidity, and a great number of them have developed antibiotic resistance. In the past recent years a new way of dealing with this problem has been studied: photodynamic inactivation. This method is based on administration of a photosensitizing substance that fixes itself in the bacterial cell followed by exposure to a light source. In the experiments done by many researchers on photodynamic inactivation of bacteria, both coherent and non-coherent light sources were used. This article is a review of these light sources and of some experimental results obtained by different authors.
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