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Updated: Jul 3, 2026

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
Published on: August 15, 2018
[Delayed cord clamping in the interest of the newborn child]
1Leids Universitair Medisch Centrum, afd. Obstetrie, K6-26, Postbus 9600, 2300 RC Leiden. s.scherjon@lumc.nl
Insights
Delayed umbilical cord clamping benefits newborns by preventing anemia and reducing blood transfusions. This practice increases neonatal blood volume and supports physiological transition without noted maternal or infant disadvantages.
Area of Science:
- Neonatal Medicine
- Obstetrics
- Pediatric Hematology
Background:
- Delayed umbilical cord clamping is increasingly recognized for its benefits in newborns.
- Studies and meta-analyses support its role in preventing neonatal anemia and reducing transfusion needs.
- Physiological rationale includes a potential 32% increase in neonatal blood volume.
Discussion:
- Evidence from controlled studies and meta-analyses supports delayed clamping for preventing neonatal anemia and reducing transfusion needs.
- No increased risks of polycythemia or hyperbilirubinemia are observed in preterm neonates; intracranial hemorrhage incidence is reduced.
Key Insights:
- Delayed umbilical cord clamping is crucial for both preterm and term infants, improving hemoglobin levels and overall neonatal health.
- Maternal outcomes are not negatively impacted by this delayed clamping procedure.
Outlook:
- Recommended standard practice: delay umbilical cord clamping for at least 3 minutes post-birth.
- A minimum 30-second delay is advised for infants requiring more immediate attention, ensuring optimal hemoglobin levels.
Abstract:
The importance of delayed cord clamping, both for the preterm and for the term newborn, for the prevention ofneonatal anaemia (during the neonatal period and/or at the age of3 months) and furthermore to reduce the need of blood transfusions, has recently been demonstrated in controlled clinical studies and meta-analyses. Physiological and pathophysiological factors also provide a rationale for delayed cord clamping: neonatal blood volume may increase by 32% if cord clamping is delayed until the umbilical cord has completely stopped pulsating. A slow transition, involving closure of the ductus arteriosus and the foramen ovale cordis and gradual filling of the neonatal systemic circulation, contributes to the opening of the alveoli due to perfusion of the alveolar capillaries. No disadvantages, such as polycythaemia or hyperbilirubinaemia, have been described with regard to preterm neonates, whereas the incidence of intracranial haemorrhages is reduced. Also for the mother, no disadvantages of late clamping have been determined. As a standard procedure, the baby's umbilical cord should not be clamped until at least 3 minutes have passed. One should wait at least 30 seconds during the birth of children for whom a more active approach is necessary. Of all people, these children will benefit from a good Hb level.

